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Anba Pharma Etoricoxib CAS No.: 202409-33-4 .. Product #: Anba-000571 Regular price: $167.00 $167.00


Catalog No.: Anba-000571
Weight: 10mg

Price: $167.00

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Etoricoxib is a synthetic, nonsteroidal anti-inflammatory drug (NSAID) with antipyretic, analgesic, and potential antineoplastic properties. Etoricoxib specifically binds to and inhibits the enzyme cyclooxygenase-2 (COX-2), resulting in inhibition of the conversion of arachidonic acid into prostaglandins. Inhibition of COX-2 may induce apoptosis and inhibit tumor cell proliferation and angiogenesis.

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2: Lories RJ. Etoricoxib and the treatment of ankylosing spondylitis. Expert Opin Drug Metab Toxicol. 2012 Dec;8(12):1599-608. doi: 10.1517/17425255.2012.741120. Epub 2012 Nov 6. Review. PubMed PMID: 23126318.
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5: Croom KF, Siddiqui MA. Etoricoxib: a review of its use in the symptomatic treatment of osteoarthritis, rheumatoid arthritis, ankylosing spondylitis and acute gouty arthritis. Drugs. 2009 Jul 30;69(11):1513-32. doi: 10.2165/00003495-200969110-00008. Review. PubMed PMID: 19634927.
6: Clarke R, Derry S, Moore RA, McQuay HJ. Single dose oral etoricoxib for acute postoperative pain in adults. Cochrane Database Syst Rev. 2009 Apr 15;(2):CD004309. doi: 10.1002/14651858.CD004309.pub2. Review. Update in: Cochrane Database Syst Rev. 2012;4:CD004309. PubMed PMID: 19370600.
7: Chilet-Rosell E, Ruiz-Cantero MT, Horga JF. Women's health and gender-based clinical trials on etoricoxib: methodological gender bias. J Public Health (Oxf). 2009 Sep;31(3):434-45. doi: 10.1093/pubmed/fdp024. Epub 2009 Mar 14. Review. PubMed PMID: 19287020.
8: Takemoto JK, Reynolds JK, Remsberg CM, Vega-Villa KR, Davies NM. Clinical pharmacokinetic and pharmacodynamic profile of etoricoxib. Clin Pharmacokinet. 2008;47(11):703-20. Review. PubMed PMID: 18840026.
9: Chen YF, Jobanputra P, Barton P, Bryan S, Fry-Smith A, Harris G, Taylor RS. Cyclooxygenase-2 selective non-steroidal anti-inflammatory drugs (etodolac, meloxicam, celecoxib, rofecoxib, etoricoxib, valdecoxib and lumiracoxib) for osteoarthritis and rheumatoid arthritis: a systematic review and economic evaluation. Health Technol Assess. 2008 Apr;12(11):1-278, iii. Review. PubMed PMID: 18405470.
10: Yuan Y, Hunt RH. Global gastrointestinal safety profile of etoricoxib and lumiracoxib. Curr Pharm Des. 2007;13(22):2237-47. Review. PubMed PMID: 17691997.
11: Capone ML, Tacconelli S, Patrignani P. Clinical pharmacology of etoricoxib. Expert Opin Drug Metab Toxicol. 2005 Aug;1(2):269-82. Review. PubMed PMID: 16922642.
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CAS Num 202409-33-4
Chemical Formula C18H15ClN2O2S
Molecular Weight 358.8419
IUPAC Chemical Name 5-Chloro-6'-methyl-3-[4-(methylsulfonyl)phenyl]-2,3'-bipyridine
Exact Mass 358.0543
Elemental Analysis C, 60.25; H, 4.21; Cl, 9.88; N, 7.81; O, 8.92; S, 8.94
Synonym Etoricoxib, Arcoxia, L-791456, MK 0663, MK-0663
Solubility Soluble in DMSO, not in water
SMILES Code O=S(C1=CC=C(C2=CC(Cl)=CN=C2C3=CC=C(C)N=C3)C=C1)(C)=O
Targets and Effects COX-2 inhibitor
Pathways Apoptosis
Appearance Solid powder
Purity >98% (or refer to the Certificate of Analysis)
Shipping Condition Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Shelf Life >2 years if stored properly

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Anba Pharma Company
3-H Gill Street, Suite 300
Woburn, MA 01801
United State

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