1: Ford CE, Ekström EJ, Howlin J, Andersson T. The WNT-5a derived peptide, Foxy-5, possesses dual properties that impair progression of ERalpha negative breast cancer. Cell Cycle. 2009 Jun 15;8(12):1838-42. Review. Retraction in: Andersson T, Ford CE, Ekström EJ, Howlin J. Cell Cycle. 2011 Apr 1;10(7):1167. PubMed PMID: 19448401.
2: Säfholm A, Tuomela J, Rosenkvist J, Dejmek J, Härkönen P, Andersson T. The Wnt-5a-derived hexapeptide Foxy-5 inhibits breast cancer metastasis in vivo by targeting cell motility. Clin Cancer Res. 2008 Oct 15;14(20):6556-63. doi: 10.1158/1078-0432.CCR-08-0711. PubMed PMID: 18927296.
3: Andersson T, Ford CE, Ekström EJ, Howlin J. Retracted manuscript: The WNT-5a derived peptide, Foxy-5, possesses dual properties that impair progression of ERα negative breast cancer. Cell Cycle. 2011 Apr 1;10(7):1167. PubMed PMID: 21430443.
4: Mehdawi LM, Prasad CP, Ehrnström R, Andersson T, Sjölander A. Non-canonical WNT5A signaling up-regulates the expression of the tumor suppressor 15-PGDH and induces differentiation of colon cancer cells. Mol Oncol. 2016 Nov;10(9):1415-1429. doi: 10.1016/j.molonc.2016.07.011. PubMed PMID: 27522468.
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Chemical
CAS Num	881188-51-8
Chemical Formula	C26H42N6O12S2
Molecular Weight	694.772
IUPAC Chemical Name	(2S,5S,8R,14S)-5-(2-carboxyethyl)-14-((S)-2-formamido-4-(methylthio)butanamido)-2-isobutyl-8-(mercaptomethyl)-4,7,10,13-tetraoxo-3,6,9,12-tetraazahexadecanedioic acid
Exact Mass	694.2302
Elemental Analysis	C, 44.95; H, 6.09; N, 12.10; O, 27.63; S, 9.23
Synonym	Foxy-5; Foxy 5; Foxy5
Solubility	Soluble in DMSO
SMILES Code	CC(C)C[C@@H](C(O)=O)NC([C@H](CCC(O)=O)NC([C@H](CS)NC(CNC([C@H](CC(O)=O)NC([C@H](CCSC)NC=O)=O)=O)=O)=O)=O
Biological
Targets and Effects	N/A
Pathways	Apoptosis
Physical
Appearance	Solid powder
Purity	>98% (or refer to the Certificate of Analysis)
Shipping Condition	Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition	Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Shelf Life	>2 years if stored properly